WLM ID: aknq | Catalog Record
Nikethamide (nicotinic acid diethylamide) was first described in 1922. It was made by the Swiss pharmaceutical firm, Ciba, and sold under the trade name Coramine. It stimulated both the circulatory and respiratory systems, and was used to counteract drug overdose. In the 1930s, Dr. Paul M. Wood (1894-1963) conducted research with this and other central nervous system stimulants, studying their use for resuscitation and for shortening the duration of anesthesia. The later development of improved ventilation techniques provided safer and more effective means for these purposes.